P9532
Sigma
Bis(polyethylene glycol bis[imidazoyl carbonyl])
| Synonym: | Bis(polyoxyethylene bis[imidazoyl carbonyl]) |
| MDL number: | MFCD00132030 |
Description
| Application | A homobifunctional, long chain cross-linking reagent. Reacts with primary amines resulting in a moderately stable carbamate linkage. Variations of this compound have been used to prepare protein conjugates. |
| Preparation Note | Prepared from PEG Compound, a tetravalent polyethylene glycol derivative, M.W. approx. 20,000. |
Properties
| form | powder |
| solubility | H2O: ≥10 mg/mL |
| methylene chloride: ≤30 mg/mL | |
| storage temp. | −20°C |
Safety
| Personal Protective Equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
| WGK Germany | 3 |
References
| reference | Beauchamp, C.O., et al., A new procedure for the synthesis of polyethylene glycol-protein adducts; effects on function, receptor recognition, and clearance of superoxide dismutase, lactoferrin, and alpha 2-macroglobulin. Anal. Biochem. 131, 25-33, (1983) Abstract |
